The American Bullmastiff Association is participating in a clinical research study at this time to hopefully find a DNA test to determine mode of inheritance. We are fortunate to have one of the country’s leading cardiologists (Dr. Joshua Stern, PhD, DVM ACVIM) conduct this study. The findings are categorized as such:
1. Affected – Doppler velocity of 2.5 or higher - Affected dogs should not be used in any breeding program. There may or may not be structural changes present.
2. Equivocal – Soft murmur with Doppler velocity of 2.0 to 2.5 – this is often the case more than not and needs careful screening. An equivocal dog may have a soft murmur at rest or a mild increase in intensity with exercise. Structural changes to the heart would lead to not using this dog in a breeding program. If no structural changes are evident, these dogs MAY be used in a breeding program but there is a RISK involved. These dogs should be bred to unaffected dogs.
3. Unaffected – No detectable murmur and flow velocity of 2.0 or below.